Scarlets have won their last three fixtures in all competitions at Parc y Scarlets but have not won four in a row at the venue since the start of last season.
Glasgow Warriors have won their last three matches in the Guinness PRO12 since their 17-22 home reversal to Ulster on 23 September.
The Scotsmen's solitary defeat on the road in the Championship this season came on a visit to Cardiff Blues in round 3.
The two sides met on four occasions last season in all tournaments with Scarlets only success being 16-10 at Scotstoun in the opening round of Guinness PRO12 play.
The Scotsmen have won on three of their last four visits to Llanelli.
Overall Guinness PRO12 head to head record:
Played 26, Scarlets won 12, Warriors won 14.
At Parc y Scarlets 7.35pm. Live on S4C and BBC Alba
Referee: Gary Conway (IRFU, 25th competition game)
Assistant Referees: David Wilkinson (IRFU) Neil Jones (WRU)
Citing Commissioner: Aurwell Morgan (WRU)
TMO: Olly Hodges (IRFU)
Suite 208, Alexandra House,
Ballsbridge, Dublin 4, Ireland