The Scotsmen's record in their last eight matches at Murrayfield in all tournaments is an even won four, lost four, whilst they have not beaten an Irish province anywhere since October 2015.
Ulster Rugby began their 2016/17 Guinness PRO12 campaign with victories in the first five rounds but have now tripped up to fellow Irish provinces Connacht and Munster in rounds 6 and 7.
The Ulstermen have won three of their last four encounters with Scottish opponents.
Ulster have lost just one of their last six matches against Edinburgh: 10-16 at Murrayfield in this equivalent fixture in round 4 last season.
Overall Guinness PRO12 head to head record:
Played 27, Edinburgh won 9, Ulster won 18.
At BT Murrayfield, 7:35pm. Live on BBC Alba & BBC NI
Referee: Andrew Brace (IRFU, 15th competition game)
Assistant Referees: Dudley Phillips (IRFU), Lloyd Linton (SRU)
Citing Commissioner: John Kirk (SRU)
TMO: Gareth Simmonds (WRU)
Suite 208, Alexandra House,
Ballsbridge, Dublin 4, Ireland